Naloxone Hydrochloride Injection Prefilled Syringe 2 mg Per 2 mL (Needle Not Included)

Naloxone Hydrochloride Injection Prefilled Syringe 2 mg per 2 mL by Endo USA is a life-saving medication designed to counteract the effects of opioid overdose swiftly. This prefilled syringe, without a needle, provides an immediate solution to reverse respiratory depression caused by opioid toxicity.

Product Details and Features:

• Concentration: 2 mg of Naloxone Hydrochloride per 2 mL, delivering a potent dose for rapid intervention.
• Prefilled Syringe: Ready-to-use format ensures quick administration in emergency scenarios.
• Needle Not Included: Allows compatibility with various needle types as per medical preference.
• Reliable Manufacturer: Produced by Endo USA, a trusted name in pharmaceutical excellence.
• Portable Design: Compact and easy to carry, making it ideal for emergency kits.

Mechanism of Action:

Naloxone Hydrochloride acts as an opioid antagonist, binding to opioid receptors in the central nervous system. It displaces opioids from these receptors, rapidly reversing their effects, particularly respiratory depression, which is crucial in an overdose situation.

Directions for Use:

1. Preparation:

   • Attach an appropriate needle to the prefilled syringe.
   • Ensure aseptic conditions to maintain sterility.

2. Administration:

   • Inject intravenously, intramuscularly, or subcutaneously as per medical guidance.
   • Administer 2 mg (2 mL) initially, and repeat doses if necessary based on the patient’s response.

3. Monitoring:

   • Continuously monitor the patient's respiratory and neurological status post-administration.

Side Effects:

• Common Side Effects:

  • Nausea
  • Vomiting
  • Sweating
  • Tachycardia
  • Tremors

• Severe Side Effects:

  • Hypotension or hypertension
  • Cardiac arrhythmias
  • Seizures
  • Pulmonary edema

Seek medical assistance if severe side effects occur.

Warnings:

• Medical Supervision: Administer under the supervision of healthcare professionals experienced in managing opioid overdoses.
• Opioid Withdrawal: Rapid reversal may cause acute withdrawal symptoms in opioid-dependent individuals.
• Multiple Doses: Be prepared to administer additional doses if the response is inadequate or if there is a reoccurrence of symptoms.
• Storage: Store in a controlled room temperature environment away from light and moisture.
• Emergency Protocols: Have resuscitative measures and supportive care readily available.

Naloxone Hydrochloride Injection by Endo USA is an essential resource in combating opioid overdoses, providing healthcare professionals with a critical tool for emergency intervention and patient safety.