Sodium Bicarbonate Injection 4.2% Single-Dose Vials 5 ml x 25/Tray by Pfizer (RX)

Sodium Bicarbonate Injection 4.2% is used to treat metabolic acidosis, a condition characterized by an excessive acid buildup in the body, often seen in conditions like renal failure and diabetic ketoacidosis. It works by restoring the body's pH balance, thereby stabilizing physiological functions. Additionally, it's used in certain drug overdoses and hyperkalemia to buffer excess acid and improve cardiac function. This injection plays a critical role in emergency medicine, helping manage severe acid-base imbalances and enhancing patient recovery prospects.

Sodium Bicarbonate Injection 4.2% by Pfizer Injectables is a critical therapeutic agent designed to swiftly correct acid-base imbalances in the body. Presented in convenient single-dose 5 ml vials, and offered in trays of 25, this injection is essential for managing metabolic acidosis in acute care settings. Renowned for its reliability and efficiency, this product is highly valued in emergency medicine, intensive care, and surgical contexts. Assembled by Pfizer, a pioneer in pharmaceutical standards, each vial delivers unmatched quality and precision necessary for urgent medical interventions.

Product Details and Features:

• Concentration and Composition: Each single-dose vial contains a 4.2% solution of sodium bicarbonate, providing immediate action against acidotic imbalances typically found in emergency care conditions.
  
• Convenient Packaging: Comes in 5 ml single-dose vials packaged in a tray of 25, offering ample supply for high-demand environments while ensuring quick access and ease of use for medical personnel.
  
• Crucial Indications: Used effectively to manage conditions such as metabolic acidosis following cardiac arrest, severe dehydration, lactic acidosis, and certain drug intoxications where acidemia has developed.

Mechanism of Action:

Sodium Bicarbonate functions by rapidly increasing plasma bicarbonate levels, which subsequently buffers excess hydrogen ions, and elevates blood pH toward the normal range. This elevation in plasma bicarbonate helps in converting metabolic acidosis into a more manageable physiologic state, allowing normal cellular metabolism to function effectively. Sodium bicarbonate acts as an alkalizing agent, neutralizing the excess acids present in the blood, thus counterbalancing conditions that are acidosis-driven.

Warnings:

• Use with Caution: Extra precaution in patients with conditions that confer sodium sensitivity, such as those with hypertension, fluid retention states, or renal impairment where sodium load exacerbation can worsen clinical status.
  
• Intravenous Use: Only to be administered intravenously by trained healthcare professionals in controlled clinical settings to avoid risks associated with extravasation or compromised dosing.
  
• Ongoing Monitoring: Patients should be closely monitored with frequent blood gas readings and electrolyte assessments to tailor dosage and prevent complications, particularly in emergency scenarios.

Side Effects:

While essential and generally well-tolerated, sodium bicarbonate injection can have some side effects:

• Common Side Effects: Metabolic alkalosis, hypocalcemia, hypokalemia. Symptoms might manifest as confusion, irritability, or tingling sensations, requiring electrolyte monitoring.
  
• Severe Side Effects: Excessive or inappropriate use can result in serious alkalosis, tissue irritation at the injection site, diuresis, or adverse shifts in sodium and fluid balance, necessitating immediate medical intervention.
  
• Systemic Effects: Overcorrection can impair tissue oxygenation or increase cardiac irritability, demanding tailored electrolytic and hemodynamic surveillance for prompt identification and rectification.

In critical care management, Sodium Bicarbonate Injection 4.2% by Pfizer Injectables stands as an indispensable resource, allowing healthcare providers to deliver precise, life-sustaining treatments. Meticulously designed for rapid deployment in acidotic emergencies, it remains a vital tool in the armamentarium of modern medicine, adding value and capability in the pursuit of superior patient care and outcomes.