Duraclon Clonidine HCl for Injection 100 mcg / mL Preservative Free 10 mL (RX)
(Note: We don’t Fill Personal Prescriptions)
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Duraclon is a medication used for the treatment of severe pain, particularly for cancer-related pain. It contains the active ingredient clonidine hydrochloride, which is an alpha-2 agonist that works by acting on the central nervous system to reduce the transmission of pain signals. This medication is administered by injection and comes in a concentration of 100 mcg/mL, with each vial containing 10 mL of solution. It is also preservative-free, which means it is less likely to cause reactions or irritate the injection site. Duraclon is only available by prescription and should only be used under the supervision of a healthcare professional.
Mechanism for Action for Duraclon Clonidine HCl for Injection 100 mcg:
Duraclon Clonidine HCl for Injection contains the active ingredient clonidine hydrochloride, which is a centrally acting alpha-2 agonist. It acts primarily on the alpha receptors in the brain and spinal cord, leading to a decrease in sympathetic nerve activity and a subsequent decrease in peripheral vascular resistance, blood pressure, and heart rate.
The exact mechanism of action of clonidine is not fully understood, but it is believed to work by stimulating alpha-2 adrenergic receptors in the pre- and postsynaptic regions of the neurons in the sinoatrial node and cardiac glial cells. This decreases the release of noradrenaline and adrenaline (epinephrine), which are potent vasoconstrictors, resulting in the reduced activation of the sympathetic nervous system and peripheral vasodilation.
Additionally, clonidine is thought to stimulate alpha-2 receptors in the brain, leading to reduced activity in the locus ceruleus, a region responsible for the arousal and fear response, and ultimately producing sedative effects.
These combined effects result in a decrease in blood pressure, heart rate, and levels of noradrenaline and adrenaline in the body. This helps to alleviate symptoms of conditions such as hypertension and opioid withdrawal, for which Duraclon Clonidine HCl for Injection is commonly used.