Solu-Medrol Injection 40 mg Single-dose Act-O-Vial System Vials 25/Tray by Pfzier (RX)

Solu-Medrol for Injection 40 mg is a corticosteroid medication used to reduce inflammation and alleviate symptoms in a variety of conditions, such as allergies, arthritis, asthma, and autoimmune disorders. It works by suppressing the immune system's response, thereby decreasing inflammation and relieving associated pain and swelling. Solu-Medrol is often used for short-term treatment and can be administered intravenously or intramuscularly, depending on the condition being treated.

Solu-Medrol (methylprednisolone sodium succinate) Injection is a corticosteroid medication formulated by Pfizer Injectables. It is used for its anti-inflammatory and immunosuppressive properties and comes in a convenient single-dose Act-O-Vial system. Each vial contains 40 mg of the active ingredient and is used in the treatment of various conditions such as allergic reactions, autoimmune diseases, and severe inflammation. The packaging configuration is 25 vials per tray.

Details and Features:

Active Ingredient: Methylprednisolone sodium succinate (40 mg per vial).
Formulation: Lyophilized powder for reconstitution and injection, provided in the Act-O-Vial system for ease of use.
Presentation: Single-dose Act-O-Vial with easy mixing to ensure proper reconstitution.
Packaging: 25 vials per tray, useful for medical facilities requiring multiple doses.
Application: Administered intravenously or intramuscularly, depending on the medical indication.
NDC: 0009-0039-28
UPC: 300090039288

Mechanism of Action:

Solu-Medrol is a synthetic glucocorticoid that mimics the action of cortisol, a natural hormone produced by the adrenal cortex. It works by:

• Reducing Inflammation: Inhibits multiple inflammatory cytokines, decreasing the inflammatory response in tissues.
  
• Immune System Suppression: Alters the body's immune response to various stimuli, making it effective in treating autoimmune and inflammatory conditions.
  
• Metabolic Effects: Regulates the metabolism of proteins, carbohydrates, and fats.

Side Effects:

Common side effects may include:

• Increased appetite and weight gain.
  
• Insomnia.
  
• Mood changes such as anxiety or depression.
  
• Elevated blood sugar levels.
  
• Acne or skin rashes.

Serious side effects may include:

• Risk of infections due to immune suppression.
  
• Osteoporosis or decreased bone density with long-term use.
  
• Peptic ulcers.
  
• Blood clots.
  
• Adrenal suppression, leading to decreased natural steroid production.

Warnings:

• Infections: Due to its immunosuppressive action, patients may be at an increased risk for infections. Use cautiously in individuals with existing infections.
  
• Long-term Use: Can lead to complications such as osteoporosis, adrenal insufficiency, and metabolic changes. Monitor regularly if extended use is required.
  
• Abrupt Withdrawal: Gradual dose reduction is essential to prevent withdrawal symptoms and adrenal insufficiency.
  
• Diabetes Caution: May require adjustments in diabetic treatment because corticosteroids can elevate blood glucose levels.
  
• Psychological Reactions: Monitor for possible psychiatric effects, particularly in individuals with a history of mental health issues.

Solu-Medrol Injection is a potent therapeutic option for managing acute situations requiring rapid intervention of inflammation or immune modulation. Clinical decision-making should include a comprehensive assessment of patient history and ongoing monitoring for side effects.