Difucan (Fluconazole Tablets) 100 mg, 30/Bottle by Pfizer USPG

Diflucan (fluconazole) Tablets are used to treat and prevent a variety of fungal infections. They are commonly prescribed for infections such as vaginal yeast infections, thrush (oral candidiasis), and systemic infections like cryptococcal meningitis. Fluconazole works by inhibiting fungal cell membrane formation, thus stopping the growth and spread of the fungus. It offers an effective oral treatment option and is often chosen for its broad-spectrum antifungal activity. As it can interact with other medications, monitoring by healthcare professionals is advised.

Pfizer USPG presents Diflucan (Fluconazole Tablets), a trusted antifungal medication designed to effectively treat a variety of fungal and yeast infections. Each bottle contains 30 tablets of 100 mg fluconazole, providing a comprehensive solution for healthcare providers and patients seeking a reliable treatment for conditions such as candidiasis and specific types of systemic fungal infections. Renowned for its efficacy and ease of use, Diflucan stands as a leading choice in antifungal therapy, underscoring Pfizer USPG's commitment to quality and patient care.

Product Details and Features:

Active Ingredient: Each tablet contains 100 mg of fluconazole, an azole antifungal agent that offers broad-spectrum activity against diverse fungal pathogens.
Packaging: Supplied in a bottle containing 30 tablets, designed for patient convenience and adherence to prescribed treatment regimens.
Indications: Primarily indicated for the treatment of infections caused by Candida, including but not limited to oropharyngeal, esophageal, and systemic candidiasis. It is also used in the treatment of cryptococcal meningitis and other specific systemic fungal infections.
Dosage and Administration: The oral tablet form facilitates straightforward dosing, making it suitable for a wide range of clinical scenarios and patient needs.
Pfizer Trust: Manufactured by Pfizer, a leader in pharmaceuticals, ensuring a product that adheres to stringent quality and safety standards.

Mechanism of Action:

Fluconazole works by inhibiting the enzyme cytochrome P450 14α-demethylase, which is necessary for converting lanosterol to ergosterol, an essential component of the fungal cell membrane. By disrupting ergosterol synthesis, fluconazole compromises the integrity of the fungal cell membrane, leading to cell death and effective resolution of the infection. Its high specificity for fungal compared to mammalian cytochromes ensures lower toxicity and high efficacy.

Warnings:

• Hepatotoxicity: Monitoring of liver function is recommended for patients on extended therapy, as fluconazole can cause liver damage in rare cases.
  
• QT Prolongation: Use caution in patients with proarrhythmic conditions, or those taking other drugs known to affect cardiovascular conduction.
  
• Hypersensitivity: Contraindicated in individuals with known hypersensitivity to fluconazole or related azole antifungals.
  
• Pregnancy and Breastfeeding: While there are specific scenarios where its use is justified, fluconazole is generally not recommended during pregnancy, particularly in high doses, due to potential teratogenic effects.

Side Effects:

Common side effects may include:

• Nausea
  
• Headache
  
• Abdominal pain
  
• Diarrhea

Serious side effects needing immediate medical attention include:

• Signs of liver dysfunction (e.g., yellowing of the skin or eyes, dark urine)
  
• Severe skin rashes, which may indicate Stevens-Johnson syndrome or toxic epidermal necrolysis
  
• Significant cardiac symptoms like palpitations or syncope that may suggest QT prolongation

Conclusion:

Diflucan (Fluconazole Tablets) by Pfizer USPG exemplifies a gold standard in antifungal treatment, offering powerful therapeutic benefits backed by robust clinical evidence. With its reliable formulation, comprehensive indications, and Pfizer’s dedication to delivering exceptional pharmaceutical care, Diflucan is poised as an essential part of the therapeutic arsenal for fungal infections. Always consult a healthcare professional to ensure its appropriate integration into patient care plans.