Bicillin C-R 900/300 Penicillin G Bezathine & Penicillin G Procaine For Injection Prefilled Syringes 2 mL x 10, Adult (Rx) **Refrigerated**

Bicillin C-R 900/300, a combination of Penicillin G Benzathine and Penicillin G Procaine, is used to treat moderate to severe infections caused by penicillin-sensitive microorganisms. This injection is especially effective against respiratory tract infections, skin and soft tissue infections, and certain sexually transmitted infections like syphilis. The combination allows for both immediate- and prolonged-release action, ensuring sustained antibiotic levels in the body. It helps eliminate bacteria, reduce infection spread, and alleviate symptoms, thus supporting faster recovery and preventing complications.

Refrigerated Item, Ships Next Day Air, Signature Required ***Note : Non-Returnable Item

Bicillin C-R 900/300 is a combination antibiotic injection that contains Penicillin G Benzathine and Penicillin G Procaine. This formulation is designed to provide both rapid and prolonged antibacterial action, making it effective in treating a variety of bacterial infections. Delivered in prefilled 2 mL syringes, it is convenient for adult administration, offering precise dosing and enhanced compliance in both outpatient and inpatient care settings. Each pack contains 10 prefilled syringes, ensuring an adequate supply for treatment courses as prescribed by a healthcare professional.

Details and Features:

• Dual Penicillin Combination: Each 2 mL injection delivers 900,000 units of Penicillin G Benzathine and 300,000 units of Penicillin G Procaine, coupling immediate action with extended-release properties for a sustained antibacterial effect.
  
• Prefilled Syringes: Designed for ease of use and accurate dosing, reducing the risk of dosing errors.
  
• Indications: Effective for the treatment of moderate to severe infections caused by penicillin-sensitive microorganisms, including certain streptococcal infections and skin infections.
  
• Convenience: Ready-to-use prefilled syringe format eliminates the need for measuring and mixing, streamlining the administration process.

Mechanism of Action:

Penicillin G Benzathine and Penicillin G Procaine exert bactericidal effects by interfering with bacterial cell wall synthesis. This disruption leads to cell wall leakage and ultimately bacterial cell death. Penicillin G Benzathine provides an extended duration of activity, maintaining therapeutic drug levels over an extended period, while Penicillin G Procaine acts quickly to deliver immediate results.

Warnings:

• Allergy Alert: Contraindicated in patients with a history of hypersensitivity to penicillins. Anaphylactic reactions can occur, and emergency treatment should be accessible during administration.
  
• Renal Impairment: Dose adjustments may be necessary for patients with significant renal dysfunction. Monitoring of renal function is advisable.
  
• Central Nervous System: High serum concentrations can result in neurotoxic reactions, including convulsions; caution is advised.
  
• Drug Interactions: Use with caution in combination with other medications, as interactions can potentiate toxicity or reduce efficacy.

Side Effects:

• Common Side Effects: Include pain at the injection site, mild skin reactions, and pruritus.
  
• Serious Side Effects: Anaphylaxis, serious hypersensitivity reactions, seizures, and neutropenia.
  
• Gastrointestinal: Some patients may experience nausea, vomiting, and diarrhea.
  Hematologic: Rarely, hemolytic anemia or thrombocytopenia can occur.

Bicillin C-R 900/300 offers a robust solution for bacterial infections requiring penicillin treatment, combining immediate action with prolonged coverage. Medical professionals must adhere strictly to usage guidelines and monitor patients closely for adverse reactions to optimize therapeutic benefits while minimizing risks.