Dexmedetomidine Injection 400 mcg Per mL Multiple-Dose Vials 4 mL by Somerset 4/Box (RX)

Discover effective sedation management with Somerset Pharma’s Dexmedetomidine Injection, a pharmaceutical-grade sedative indicated for various clinical settings. Dexmedetomidine 400 mcg/mL offers clinicians precise control and a reliable option for sedation without respiratory depression typically observed in other sedatives. Ideal for use in an ICU or surgical setting, this product provides the desired level of sedation while enabling swift patient recovery and discharge post-procedure. Packaged in a convenient box containing four 4 mL multiple-dose vials, it assures both efficacy and reliable availability for healthcare providers.

Details and Features:

Brand: Somerset Pharma
Concentration: 400 mcg/mL
Volume: 4 mL per vial
Packaging: 4 vials per box
Formulation: Clear, sterile solution
Indications: Intended for sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, and for sedation of non-intubated patients prior to and/or during surgical and other procedures.

Mechanism of Action:

Dexmedetomidine acts as a selective alpha-2 adrenergic receptor agonist. By stimulating these receptors, it inhibits the release of norepinephrine, which leads to sedative and anxiolytic effects. The drug’s action centrally modulates sympathetic activity, providing sedation resembling natural sleep without causing significant respiratory depression. This unique effect profile makes it especially suitable for settings where patient safety and flexible sedation levels are paramount.

Directions:

Administration: Dexmedetomidine should be administered intravenously. It may be diluted prior to infusion depending on clinical protocols.
Dosage Adjustment: Tailor the dosage to the patient's health status, weight, and sedation need. Precise dosing should follow institution-specific protocols.
Professional Use Only: Administration should be conducted only by specifically trained healthcare professionals in a suitable monitoring setting.

Warnings:

• Monitoring: Continuous cardiac and oxygen saturation monitoring is recommended during administration, due to the risk of bradycardia and hypotension.
  
• Patients with Hepatic Dysfunction: Adjust doses carefully.
  
• Pregnancy and Lactation: Use only if clearly needed, as data is limited regarding its safety in pregnant or nursing mothers.
  
• Avoid Abrupt Withdrawal: A gradual reduction in dosage is advised when discontinuing the infusion to prevent potential hemodynamic instability.
  
• Contraindications: Known hypersensitivity to dexmedetomidine or any components of the formulation.

Side Effects:

While generally well-tolerated, possible side effects may include:

• Cardiovascular:  Bradycardia, hypotension, or hypertension (less common during infusion).
  
• Neurological: Dizziness, confusion, or other CNS depressant effects when combined with similar agents.
  
• Others: Dry mouth, nausea, or transient hypertension.

Somerset Pharma's Dexmedetomidine Injection provides an advanced tool for sedation with a safety profile that reduces respiratory concerns. Its efficiency in ICU sedation protocols and procedural sedation makes it an indispensable choice for medical professionals aiming for quality patient care.