Lidocaine Hydrochloride 1% Injection 20 mL Multipe Dose Vial 25/Pack by Pfizer (Rx)

Lidocaine Hydrochloride 1% Injection is used as a local anesthetic to induce numbness in a specific area before minor surgical procedures, dental work, or other medical interventions. By blocking nerve signals, it helps alleviate pain and discomfort during operations. Additionally, it sometimes manages acute ventricular arrhythmias, stabilizing heart rhythms in critical cardiac situations. This versatile anesthetic provides effective sensory blockade, ensuring patient comfort and successful procedural outcomes.

Lidocaine Hydrochloride 1% Injection is a sterile, non-pyrogenic local anesthetic solution used to produce local or regional anesthesia. This formulation contains lidocaine hydrochloride at a concentration of 1% (10 mg/mL) and is intended for injection. It is packaged by Pfizer in multiple-dose vials containing 20 mL of the solution, with each pack containing 25 vials.

Details and Features:

Volume: 20 mL per vial
Packaging: 25 vials per pack
Concentration: 1% Lidocaine Hydrochloride (10 mg/mL)
Use: Local anesthetic for infiltration, nerve block, and epidural anesthesia
Sterility: The solution is sterile and non-pyrogenic
Preservative: Contains preservatives if labeled as multi-dose to allow for multiple withdrawals

Mechanism of Action:

Lidocaine is a local anesthetic of the amide type. It works by inhibiting sodium ion influx through voltage-gated sodium channels in the neuronal cell membrane. This blockade prevents the initiation and conduction of nerve impulses, effectively numbing the injected area and providing anesthesia. The onset of action is rapid, and the duration depends on the dose and concentration used.

Warnings:

• Proper Use: Should only be administered by or under the guidance of healthcare professionals experienced in the administration of local anesthetics and management of complications.
  
• Allergic Reactions: Patients with a history of hypersensitivity to amide-type local anesthetics should not use this product.
  
• Dosing Caution: Overdose or intravascular injection can lead to toxicity, potentially resulting in cardiovascular collapse, CNS disturbances, or respiratory arrest.
  Cross-Reactivity: Be cautious in patients with known drug allergies, particularly to similar anesthetics.
  
• Use in Pregnancy: Should be used during pregnancy only if clearly needed and prescribed by a healthcare professional.
  
• Multiple-Dose Vial: Contains preservatives, so adhere to strict aseptic techniques to avoid contamination.

Side Effects:

While generally well-tolerated when used correctly, lidocaine may cause side effects, particularly if administered improperly or in excessive amounts. Potential side effects include:

• Local Reactions: Pain at the injection site, swelling, or irritation
  
• Systemic Reactions: Dizziness, numbness, tingling sensations, or nervousness
  
• Cardiovascular: Hypotension, bradycardia, or cardiac arrest in severe overdoses
  
• CNS Effects: Drowsiness, seizures, tremors, or confusion
  
• Allergic Reactions: Rare but can include skin rashes or anaphylaxis

Safety Note:

Lidocaine Hydrochloride 1% Injection must be used with care following specific dosage and administration guidelines tailored to the individual’s needs and health conditions. Monitoring is essential during administration to detect and manage any adverse reactions promptly.