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Polymyxin B

Polymyxin B is an antibiotic primarily used to treat infections caused by Gram-negative bacteria. It belongs to a class of antibiotics known as polymyxins and is often used in situations where other antibiotics may not be effective. Polymyxin B disrupts the bacterial cell membrane, leading to cell death. Due to its potential nephrotoxicity (kidney damage) and neurotoxicity, systemic use is generally reserved for serious, life-threatening infections where alternative treatments are ineffective or unavailable. Its use should be carefully monitored by healthcare professionals.