Cefuroxime Axetil 250 mg Tablets (20 Count) by Ascend (RX)

Cefuroxime Axetil 250 mg Tablets are used to treat various bacterial infections including respiratory tract infections, urinary tract infections, skin infections, and Lyme disease. As a second-generation cephalosporin antibiotic, Cefuroxime Axetil is effective against both Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial cell wall synthesis, leading to the death of the bacteria. This antibiotic is often prescribed to alleviate symptoms, prevent complications, and promote recovery in infections that are susceptible to its action.

Cefuroxime Axetil 250 mg Tablets by Ascend Laboratories is an oral antibiotic medication used to treat a variety of bacterial infections. As a second-generation cephalosporin, it is effective against a broad spectrum of gram-positive and gram-negative bacteria. This product comes in a pack of 20 tablets, suitable for short-term treatment courses for infections such as respiratory tract infections, urinary tract infections, skin infections, and Lyme disease.

Details and Features:

• Active Ingredient: Each tablet contains 250 mg of cefuroxime axetil, which is the prodrug form, converted into its active form in the body to exert its antibacterial action.
  
• Packaging: The product includes 20 tablets, often prescribed for a full treatment regimen based on the specific infection and patient needs.
  
• Indications: Primarily used for the treatment of pharyngitis/tonsillitis, acute bacterial exacerbations of chronic bronchitis (ABECB), uncomplicated skin and skin-structure infections, urinary tract infections, and early Lyme disease.
  
• Administration: The tablets are designed for oral use and can be taken with or without food, although taking them with food may improve absorption and reduce stomach upset.
  
• Broad-Spectrum Antibacterial: Effective against susceptible strains of both gram-positive and gram-negative bacteria, providing versatile treatment options.

Mechanism of Action:

Cefuroxime axetil functions by binding to penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final steps of bacterial cell wall synthesis, leading to cell lysis and death. As a result, the growth of bacteria is halted, and the infection is controlled and eventually resolved.

Warnings:

• Allergic Reactions: Contraindicated in patients with known cephalosporin hypersensitivity or a history of severe penicillin allergy due to potential cross-reactivity.
  
• Renal Impairment: Dose adjustment may be necessary for patients with significant renal dysfunction to prevent drug accumulation and toxicity.
  Clostridium difficile-Associated Diarrhea: Can occur with antibiotic therapy due to disruption of normal gut flora; immediate treatment and discontinuation may be necessary in severe cases.
  Monitoring: Patients on prolonged therapy should undergo periodic assessment of renal, hepatic, and hematopoietic functions.

Side Effects:

• Common Side Effects: Include diarrhea, nausea, vomiting, headache, dizziness, and mild skin rash.
  
• Serious Side Effects: Severe allergic reactions (anaphylaxis), severe skin reactions like Stevens-Johnson syndrome, hematologic changes such as leukopenia or thrombocytopenia, and hepatotoxicity.
  
• Gastrointestinal Effects: Risk of pseudomembranous colitis; patients should immediately inform their healthcare provider if they experience severe diarrhea.

Cefuroxime Axetil 250 mg Tablets by Ascend Laboratories provide effective oral treatment for a variety of bacterial infections. Proper usage as prescribed by a healthcare provider ensures optimal therapeutic outcomes while minimizing potential risks and adverse effects.