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Amiodarone Injection 50 mg/mL Single-Dose Vial 9 mL Vial by Fresenius (Rx)

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Original price $ 12.75
Current price $ 7.95
SKU 63323-0616-09ea
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Amiodarone Injection is used to treat and prevent life-threatening ventricular arrhythmias, such as ventricular tachycardia and ventricular fibrillation. This antiarrhythmic medication works by regulating electrical signals in the heart, helping to maintain a normal heart rhythm. It is typically administered intravenously in a hospital setting for rapid effect, especially during emergencies. Due to its potent effects and potential side effects, amiodarone requires careful monitoring by healthcare professionals to ensure safety and efficacy in stabilizing heart rhythm.

Fresenius Kabi offers Amiodarone Injection, a critical antiarrhythmic medication formulated for the acute management of life-threatening ventricular arrhythmias, including recurrent ventricular fibrillation and unstable ventricular tachycardia. Delivered in a 50 mg/mL concentration within a 9 mL single-dose vial, this medication ensures rapid and precise dosing, essential for emergency cardiac care. Relied upon in high-stakes clinical settings, Amiodarone Injection by Fresenius Kabi is a trusted choice for healthcare professionals committed to cardiac safety and efficacy.

Product Details and Features:

Active Ingredient: Each 9 mL vial contains 50 mg/mL of amiodarone hydrochloride, a potent antiarrhythmic agent used to restore normal cardiac rhythm.
Packaging: Supplied as a single-dose vial, facilitating quick handling and preparation in urgent clinical situations. This packaging ensures the maintenance of sterility and integrity for reliable dosing.
Indications: Primarily indicated for the treatment and prophylaxis of serious ventricular arrhythmias, making it indispensable in critical care and emergency medicine environments.
Quality Assurance: Manufactured by Fresenius Kabi, a leader in pharmaceutical manufacturing, known for their rigorous quality control standards and dedication to patient safety.

Mechanism of Action:

Amiodarone functions by prolonging the action potential phase and refractory period of cardiac tissue. It works across multiple channels as it blocks potassium channels, resulting in a decrease in cardiac repolarization, and extends the cardiac action potential. It also possesses sodium channel blocking properties and displays non-competitive alpha- and beta-blocking capabilities. This multifaceted mechanism stabilizes cardiac electrical activity, making it effective in controlling life-threatening arrhythmias.

Warnings:

  • Pulmonary Toxicity: Monitor for signs of pulmonary toxicity, which can be fatal. Immediate evaluation is necessary if new or worsening symptoms occur.
  • Hepatotoxicity: Routine liver function tests are advised, as amiodarone can lead to hepatic dysfunction or severe hepatic injury.
  • Arrhythmias: May exacerbate existing arrhythmias or cause new ones in some patients.
  • Thyroid Dysfunction: Monitor thyroid levels, as amiodarone can cause hypo- or hyperthyroidism.
  • Visual Impairment: Regular ophthalmic exams are recommended, as corneal deposits and optic neuropathy have been reported.

Side Effects:

Common side effects may include:

  • Bradycardia
  • Hypotension
  • Gastrointestinal disturbances, such as nausea or constipation

Serious side effects necessitating immediate medical intervention include:

  • Acute respiratory distress suggestive of pulmonary toxicity
  • Liver function abnormalities or jaundice indicating liver damage
  • Visual changes that may suggest optic neuropathy
  • Manifestations of thyroid dysfunction, such as unexplained weight loss or gain

Conclusion:

Amiodarone Injection 50 mg/mL by Fresenius Kabi is an integral solution for managing severe cardiac arrhythmias in acute care settings. Its comprehensive mechanism of action and critical role in life-saving interventions make it an indispensable resource for healthcare providers focused on achieving optimal patient outcomes in cardiac emergencies. With Fresenius Kabi's unwavering commitment to quality and safety, you can trust in the efficacy and dependability of this essential pharmaceutical product.

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