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Hylenex Injection Recombinant Hyaluronidase Human (Rx) **Refrigeration Item

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Original price $ 199.95
Current price $ 155.00
SKU 18657-0117-02vial
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Send an email request to: sales@mountainside-medical.com

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Hylenex is used to increase the absorption and dispersion of other injected medications. It contains hyaluronidase, an enzyme that helps break down hyaluronic acid in the body, facilitating the spread of fluids and medications. It's commonly used in settings where rapid drug absorption is needed or to improve the effectiveness of subcutaneous fluid administration. Always use it under the guidance of a healthcare professional.

Discover Hylenex injections for improved absorption of fluids and medications. Enhance hydration therapy and expedite drug delivery in medical treatments. Find below about Hylenex Injection uses, cost, side effects and protocol on how to use hylenex.

Note: Refrigerated Item, Ships Next Day Air, Signature Required  Someone must be available to receive this shipment.

Hylenex Injection is used to enhance the dispersion and absorption of subcutaneously injected medications. It contains hyaluronidase, an enzyme that modifies the permeability of connective tissues by hydrolyzing hyaluronic acid, a component of the extracellular matrix. Hylenex is commonly used to facilitate subcutaneous fluid administration, enhance the delivery of anesthetics, and increase the efficacy of rehydration. It is also helpful in improving the uptake of contrast agents in imaging procedures and accelerating the absorption of injected drugs.

Where do you inject Hylenex?

Hylenex is injected subcutaneously, which means just under the skin. It is commonly administered in the following areas:

  1. Abdomen: Often around the stomach area, avoiding the navel.
  2. Upper Arm: The outer aspect of the arm provides an accessible location.
  3. Thighs: Typically the front aspect, where there is more subcutaneous tissue.

The specific site may depend on the treatment plan and the patient's needs. It's important to follow medical guidance for proper injection technique and site selection. Always consult a healthcare professional for precise instructions.

How much Hylenex does it take to dissolve fillers?

The amount of Hylenex (a brand of hyaluronidase) needed to dissolve dermal fillers can vary based on several factors:
  1. Amount of Filler: The volume of filler that needs to be dissolved impacts the required dosage.

  2. Type of Filler: Different hyaluronic acid fillers may have varying cross-linking densities, affecting how easily they dissolve.

  3. Area Treated: Certain areas may require more precise applications and, therefore, varying amounts of Hylenex.

  4. Desired Outcome: The extent of correction or reversal required will also influence the quantity used.

Typically, a practitioner will start with a conservative amount and assess the effect, possibly requiring multiple sessions for optimal results. It's essential for these injections to be administered by a qualified professional to determine the appropriate dosage for each individual case.

How much does Hylenex cost?

The cost of Hylenex can vary based on several factors, including the provider, geographic location, and the setting in which it’s administered. Generally, prices can range from approximately $154 to $425 or more per treatment session. It’s important to consult with a qualified healthcare provider or clinic to get a specific quote and understand what the cost includes, such as consultation fees or follow-up appointments.

How fast does Hylenex work?

Hylenex typically begins to work quickly, often within minutes to a few hours after injection. The full effects, such as the dissolution of hyaluronic acid fillers, can generally be observed within 24 to 48 hours. However, the exact timing can vary based on factors like the amount of product used, the type and amount of filler being dissolved, and individual patient factors.

Details and Features:

Formulation: Hylenex is supplied as a clear, colorless, sterile liquid solution in a 1 mL vial containing 150 units/mL of recombinant human hyaluronidase.
Administration: Typically administered subcutaneously as part of other therapies to enhance drug absorption.
Storage: Hylenex should be stored refrigerated at 2-8°C (36-46°F).

Mechanism of Action:

Hylenex works by temporarily breaking down hyaluronic acid, a component of the extracellular matrix in tissues. Hyaluronic acid forms a barrier to the diffusion of fluids, so by decreasing its viscosity, Hylenex enhances the permeability of subcutaneous or connective tissue. This action enables faster absorption and spread of co-administered drugs or fluids injected under the skin.

Side Effects:

Potential side effects of Hylenex may include:

  • Local injection site reactions (redness, swelling, itching)
  • Mild discomfort or irritation at the injection site
  • Rare systemic allergic reactions

Warnings:

  • Hypersensitivity: Should not be used in individuals with a known allergy to hyaluronidase or any of the formulation's components.
  • Not for Direct Injection into Veins or Eyes: The enzyme is not designed for intravenous or intraocular use.
  • Pregnancy and Nursing: Consult with a healthcare provider, as the effects during pregnancy or breastfeeding are not fully established.
  • Drug Interactions: Potential interactions with other medications must be reviewed by healthcare professionals.
    Infection risk: Areas of infection or inflammation should be approached cautiously, as the enzyme may facilitate the spread of infection.

Hylenex Hyaluronidase Injection Information

What is Hylenex used for?

Hylenex is a brand name for hyaluronidase, which is an enzyme used in medical settings to help facilitate the
dispersion and absorption of fluids or medications injected into the body. It is often used to improve the absorption of other injected drugs or to help in rehydrating patients. It can also be used to increase the effectiveness of subcutaneous fluid administration in cases like hypodermoclysis (fluid replacement). Additionally, Hylenex can be used to enhance the resolution of subcutaneous and intramuscular drug infiltration.

Hylenex vs Hyaluronidase

Hylenex and hyaluronidase refer to closely related medical products, with some differences primarily in branding and formulation:

Hylenex:

  • Hylenex is a specific brand of hyaluronidase.
  • It is a recombinant human hyaluronidase, meaning it is produced using recombinant DNA technology, ensuring it is identical to the natural human enzyme.
  • Hylenex is generally used to enhance the absorption and dispersion of co-administered drugs and fluids.

Hyaluronidase:

  • This is an enzyme that breaks down hyaluronic acid, a component of the extracellular matrix.
  • The enzyme facilitates the dispersion and absorption of injected fluids and medications.
  • It can be derived from various sources, such as bovine (cow) or recombinant technology.

In summary, Hylenex is a specific formulation of hyaluronidase designed for medical use, often preferred due to its human-derived enzyme, which may reduce the risk of allergic reactions compared to animal-derived versions.

Hylenex Protocol

Hylenex, containing hyaluronidase, is
primarily used to enhance the absorption and dispersion of other injected drugs or fluids. It's often utilized in various medical scenarios, such as fluid administration, contrast agent dispersion, and subcutaneous drug delivery.

General Outline for Hylenex Usage Protocol:

Indication: Ensure verification of Hylenex's necessity for enhancing absorption of fluids or medications.

Dosage: Typically, Hylenex is administered subcutaneously with the specific dosing based on the accompanying medication or fluid's volume and concentration. Follow specific dosage guidelines as recommended by healthcare practitioners or protocols.

Administration:

  • Preparation: Confirm it's the right product and prepare the syringe with the recommended dose.
  • Injection Site: Select an appropriate injection site, usually the same site where the accompanying fluid or drug will be administered.
  • Technique: Administer Hylenex subcutaneously, ensuring aseptic techniques.

Monitoring: Observe for any
adverse reactions post-administration. These can include local reactions
like redness, swelling, or systemic effects, though they are generally
rare.

Documentation: Record the usage in the patient’s medical record, including dosage, time, and any observed reactions.

For tailored protocols, always refer to institutional guidelines or consult a healthcare professional.

Hylenex Side Effects:

Hylenex can have side effects, although not everyone experiences them. Common side effects may include:

Injection Site Reactions:

  • Redness
  • Swelling
  • Pain or tenderness

Allergic Reactions: Though rare, some individuals may experience:

  • Rash
  • Itching
  • Difficulty breathing

Other Effects:

  • Headache
  • Dizziness

It's important to monitor for any unusual symptoms after receiving Hylenex and report them to a healthcare provider. If you suspect an allergic reaction, seek medical attention immediately. Always use Hylenex under the supervision of a healthcare professional.