Hylenex Clinical Drug Information -- Hylenex Product Information
Hylenex Injection Recombinant Hyaluronidase Human (Rx) **Refrigeration Item
(Note: We don’t Fill Personal Prescriptions)
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Hylenex is used to increase the absorption and dispersion of other injected medications. It contains hyaluronidase, an enzyme that helps break down hyaluronic acid in the body, facilitating the spread of fluids and medications. It's commonly used in settings where rapid drug absorption is needed or to improve the effectiveness of subcutaneous fluid administration. Always use it under the guidance of a healthcare professional.
Discover Hylenex injections for improved absorption of fluids and medications. Enhance hydration therapy and expedite drug delivery in medical treatments. Find below about Hylenex Injection uses, cost, side effects and protocol on how to use hylenex.
Note: Refrigerated Item, Ships Next Day Air, Signature Required Someone must be available to receive this shipment.
Hylenex Injection is used to enhance the dispersion and absorption of subcutaneously injected medications. It contains hyaluronidase, an enzyme that modifies the permeability of connective tissues by hydrolyzing hyaluronic acid, a component of the extracellular matrix. Hylenex is commonly used to facilitate subcutaneous fluid administration, enhance the delivery of anesthetics, and increase the efficacy of rehydration. It is also helpful in improving the uptake of contrast agents in imaging procedures and accelerating the absorption of injected drugs.
Where do you inject Hylenex?
Hylenex is injected subcutaneously, which means just under the skin. It is commonly administered in the following areas:
- Abdomen: Often around the stomach area, avoiding the navel.
- Upper Arm: The outer aspect of the arm provides an accessible location.
- Thighs: Typically the front aspect, where there is more subcutaneous tissue.
The specific site may depend on the treatment plan and the patient's needs. It's important to follow medical guidance for proper injection technique and site selection. Always consult a healthcare professional for precise instructions.
How much Hylenex does it take to dissolve fillers?-
Amount of Filler: The volume of filler that needs to be dissolved impacts the required dosage.
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Type of Filler: Different hyaluronic acid fillers may have varying cross-linking densities, affecting how easily they dissolve.
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Area Treated: Certain areas may require more precise applications and, therefore, varying amounts of Hylenex.
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Desired Outcome: The extent of correction or reversal required will also influence the quantity used.
Typically, a practitioner will start with a conservative amount and assess the effect, possibly requiring multiple sessions for optimal results. It's essential for these injections to be administered by a qualified professional to determine the appropriate dosage for each individual case.
How much does Hylenex cost?Details and Features:
Formulation: Hylenex is supplied as a clear, colorless, sterile liquid solution in a 1 mL vial containing 150 units/mL of recombinant human hyaluronidase.
Administration: Typically administered subcutaneously as part of other therapies to enhance drug absorption.
Storage: Hylenex should be stored refrigerated at 2-8°C (36-46°F).
Mechanism of Action:
Hylenex works by temporarily breaking down hyaluronic acid, a component of the extracellular matrix in tissues. Hyaluronic acid forms a barrier to the diffusion of fluids, so by decreasing its viscosity, Hylenex enhances the permeability of subcutaneous or connective tissue. This action enables faster absorption and spread of co-administered drugs or fluids injected under the skin.
Side Effects:
Potential side effects of Hylenex may include:
- Local injection site reactions (redness, swelling, itching)
- Mild discomfort or irritation at the injection site
- Rare systemic allergic reactions
Warnings:
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Hypersensitivity: Should not be used in individuals with a known allergy to hyaluronidase or any of the formulation's components.
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Not for Direct Injection into Veins or Eyes: The enzyme is not designed for intravenous or intraocular use.
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Pregnancy and Nursing: Consult with a healthcare provider, as the effects during pregnancy or breastfeeding are not fully established.
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Drug Interactions: Potential interactions with other medications must be reviewed by healthcare professionals.
Infection risk: Areas of infection or inflammation should be approached cautiously, as the enzyme may facilitate the spread of infection.