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Manganese Chloride Injection 0.1 mg/mL SDV 10 mL x 25/Tray (RX)

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Original price $ 2,250.00
Current price $ 1,795.00
SKU 00409-4091-01
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Manganese Chloride Injection is used as a trace element supplement in total parenteral nutrition (TPN) to prevent and treat manganese deficiency. This injection is essential for individuals who cannot obtain adequate manganese through oral intake due to medical conditions or nutritional support needs. Manganese plays a crucial role in bone formation, metabolism, and antioxidant enzyme function. It is important for administering only the prescribed dosage, as excessive manganese can lead to toxicity. Healthcare professionals closely monitor manganese levels in patients receiving TPN to ensure safety.

Pfizer Injectables offers Manganese Chloride Injection, a critical trace element solution meticulously crafted for total parenteral nutrition (TPN) supplementation. Delivered in a precise concentration of 0.1 mg/mL, this product plays an essential role in maintaining metabolic balance in patients requiring intravenous nutrition. Packaged in sterile 10 mL single-dose vials arrayed in trays of 25, it provides healthcare professionals with a reliable, high-quality source of manganese, reinforcing Pfizer's commitment to excellence in patient care.

Product Details and Features:

Active Ingredient: Each 10 mL single-dose vial contains 0.1 mg/mL of Manganese Chloride, supplying an essential nutrient crucial for the functioning of several enzyme systems.
Packaging: Sold in trays containing 25 single-dose vials, ensuring convenient and aseptic use in clinical settings.
Indications: Ideal for use as a supplement to intravenous solutions for TPN, providing necessary manganese to patients unable to receive adequate nutrition through oral intake.
Quality Assurance: Manufactured by Pfizer, adhering to the highest standards of pharmaceutical quality and safety, ensuring dependable and consistent potency and purity.

Mechanism of Action:

Manganese is a vital trace element that acts as a cofactor for a variety of enzymes, including those necessary for carbohydrate, protein, and lipid metabolism. It plays a pivotal role in manganese superoxide dismutase activity, which is critical for mitigating oxidative damage within cells. By supplying manganese to patients, these vital metabolic processes are supported, helping to maintain physiological function during parenteral nutrition.

Warnings:

  • Allergic Reactions: Do not use in patients with a known hypersensitivity to manganese or any components of the injection.
  • Overdose Risk: Increased risk of manganese toxicity in patients with impaired liver function, as manganese is excreted primarily via the biliary system.
  • Clinical Monitoring: Routinely measure manganese levels in prolonged TPN administration to avoid toxicity.
  • Pregnancy and Nursing: Use with caution in pregnant or nursing women, as the safety of manganese supplementation in these groups has not been well studied.

Side Effects:

Common side effects are rare but may include:

  • Local injection site reactions.
  • Transient taste alterations.

Serious side effects, although uncommon, may necessitate medical attention:

  • Manganese toxicity may lead to symptoms such as neuropsychiatric manifestations (confusion, tremors), hepatotoxicity, or elevated serum manganese levels.
  • Signs of allergic reactions, such as rash, itching, or difficulty breathing.

Conclusion:

Manganese Chloride Injection by Pfizer Injectables represents an essential component for comprehensive nutritional therapy in patients requiring TPN. With its precise formulation and rigorous production standards, this product supports healthcare providers in optimizing patient outcomes, particularly in managing nutritional and metabolic needs with unmatched reliability.

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