Phenergan Injection (Promethazine HCL Injection) 50mg/mL Ampule 1 mL, 25/Box

Phenergan Injection (Promethazine HCL) for effective relief of allergy symptoms, nausea, and motion sickness. Supports calm and comfort.

Phenergan Injection (Promethazine HCL Injection) by Hikma Injectables offers effective relief and management for a range of ailments, designed for healthcare professionals seeking dependable solutions. Each box contains 25 ampules of 1 mL, each delivering 50 mg/mL of promethazine HCL. This injectable solution is widely used to treat allergic reactions, preoperative sedation, nausea and vomiting, and motion sickness. Trust in Phenergan for a rapid onset of action and comprehensive patient care in clinical environments.

Product Details & Features:

Concentrated Solution: Provides 50 mg/mL of promethazine HCL per 1 mL ampule, allowing for tailored dosing according to patient needs.
Versatile Applications: Utilized in various medical scenarios, including allergic reactions, nausea, vomiting, and sedation.
Sterile Packaging: Each ampule ensures sterility, preventing contamination and maintaining efficacy across diverse healthcare settings.
Quick Onset: Delivers prompt therapeutic effects suitable for acute medical situations, ensuring reliable and predictable response outcomes.
Box of 25 Ampules: Sufficient quantity ideal for sustained treatment courses or use in busy medical facilities.

Mechanism of Action:

Promethazine, the active ingredient in Phenergan Injection, functions primarily as an antihistamine and antiemetic. It works by:

• Inhibiting H1 Receptors: Blocks the action of histamine at H1 receptor sites, leading to relief from allergic symptoms such as itching, hives, and runny nose.
  
• Antiemetic Effects: Acts on the emetic center of the brain and vestibular apparatus to reduce nausea and vomiting.
  
• Sedative Properties: By blocking central nervous system dopamine receptors, it provides mild sedation useful in preparing patients for surgery or other procedures.

Directions:

1. Dosage: Administer intramuscularly or intravenously according to the specific condition being treated and patient response. Consult standard dosing guidelines or a healthcare professional.
2. Administration: Follow aseptic techniques. For IV administration, ensure proper dilution and slow injection to avoid side effects.
3. Frequency: Follow prescribed dosing schedules. Modifications may be required for patients with compromised liver or kidney function.
4. Monitor: Observe patients for effectiveness and any adverse reactions post-administration.

Warnings:

• Severe Tissue Injury: Avoid intra-arterial and subcutaneous routes due to the risk of gangrene. Intramuscular injection is preferred.
  
• Respiratory Depression: Risk increases when used with other central nervous system depressants. Monitor closely, especially in children and elderly patients.
  
• Allergies: Do not use in individuals with a known hypersensitivity to promethazine or similar compounds.
  
• Pediatric Use: Not recommended for children under 2 years due to the risk of fatal respiratory depression.

Side Effects:

While most patients tolerate Phenergan well, possible side effects include:

• Sedation and Drowsiness: Common due to CNS effects; patients should avoid driving or operating machinery.
  
• Anticholinergic Effects: May cause dry mouth, blurred vision, or urinary retention.
  
• Hypotension: Particularly when administered intravenously; ensure patients are kept hydrated and monitor blood pressure.
  
• Local Tissue Reactions: Pain, redness, or swelling may occur at the injection site.
  
• Rarely: Severe allergic reactions or neuroleptic malignant syndrome may develop, warranting immediate medical attention.

Hikma Injectables provides a trusted choice in promethazine therapy with Phenergan Injection, offering medical professionals a potent and adaptable tool for patient care.