Thiamine HCI Injection (Vitamin B1) 200 mg Per 2 mL (100 mg per mL) Multiple Dose Vials 2 mL x 25/Tray (RX)

Boost energy and improve nerve function with Thiamine Injection. Essential for metabolism, heart health, and preventing vitamin B1 deficiency.

Thiamine HCl Injection (Vitamin B1) 200 mg is used to treat and prevent thiamine deficiency, which can lead to conditions such as beriberi and Wernicke's encephalopathy. It is particularly important in patients with chronic alcoholism, malabsorption syndromes, or severe malnutrition. Thiamine is vital for carbohydrate metabolism and proper nerve function. Administered intravenously or intramuscularly, it helps restore thiamine levels rapidly, thereby preventing complications like nerve, muscle, and brain abnormalities associated with thiamine deficiency.

Details and Features

Active Ingredient: Thiamine Hydrochloride (Vitamin B1)
Concentration: 100 mg/mL
Volume: 2 mL per vial
Packaging: 25 multiple-dose vials per tray
Administration: Intramuscular (IM) or Intravenous (IV)
Indications: Used for the treatment and prevention of thiamine deficiency, which can lead to conditions such as beriberi, Wernicke's encephalopathy, and Korsakoff's syndrome. Also used in situations where there might be increased metabolic demand.

Mechanism of Action

Thiamine is a water-soluble vitamin that is essential for carbohydrate metabolism and neural function. It acts as a cofactor for several enzymes involved in the Krebs cycle and in the biochemical pathways that metabolize carbohydrates, fats, and amino acids into adenosine triphosphate (ATP), which is a crucial energy source for cells. This role is particularly critical for tissues with high energy demands such as the brain and heart.

Warnings

• Allergic Reactions: Though rare, some individuals may experience hypersensitivity reactions. Monitoring is advised during initial administrations.
  
• Intravenous Administration: Care should be taken to administer the injection slowly to minimize the risk of adverse reactions.
  
• Storage and Handling: Maintain proper storage conditions as indicated, usually at controlled room temperatures, to ensure product stability and efficacy.

Side Effects

Thiamine HCl Injection is generally well-tolerated, but some side effects may occur, especially if the injection is not administered properly:

Common Side Effects:

• Mild pain or irritation at the injection site
  
• Itching or rash

Serious Side Effects (uncommon):

• Allergic reactions, which may present as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat
  
• Anaphylaxis (though this is very rare)

Other Considerations:

• Monitoring: Ensure that treatment is conducted under the supervision of a healthcare professional, particularly in cases of severe deficiency or where IV administration is involved.
  
• Diet and Nutritional Advice: Patients should also be advised to maintain a balanced diet to prevent future deficiencies, emphasizing foods high in thiamine such as whole grains, nuts, and legumes, alongside B-complex vitamins if necessary, to support overall health.

Overall, Thiamine HCl Injection is an effective and rapid method to correct thiamine deficiency and prevent related complications, particularly in clinical settings where expedited treatment is vital. Proper administration and monitoring can mitigate most risks and enhance treatment efficacy.