Dimenhydrinate Injection is a potent prescription antiemetic supplied in a 1 mL multi-dose vial (MDV) at 50 mg per mL. It delivers rapid relief from severe nausea, vomiting, dizziness, and vertigo, especially related to motion sickness and other vestibular disorders. Each vial contains dimenhydrinate (an 8-chlorotheophylline salt of diphenhydramine) in a sterile solution with propylene glycol and a 5% benzyl alcohol preservative. Because it is an injection formulation (IM/IV), it acts faster than oral equivalents and is used when immediate effect or an alternative to oral therapy is needed. As with any powerful medication, Dimenhydrinate Injection is Rx-only and should be used under medical supervision (see Usage & Precautions below).
Uses
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Prevention and treatment of nausea, vomiting, and dizziness associated with:
- Motion sickness (travel, sea, air)
- Vestibular disorders
- Postoperative recovery (PONV)
- Medication side effects
- Radiation therapy or chemotherapy
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Suitable for emergency rooms, clinics, surgical centers, and travel medicine
Benefits
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Rapid Relief: Fast onset of action for acute nausea, vomiting, and dizziness
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Flexible Administration: Can be given IM or IV, making it versatile for a variety of clinical needs
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Multiple Dose Vials: Cost-effective packaging for busy medical or surgical offices
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Pharmacy-Grade Quality: Manufactured by Fresenius Kabi, trusted by hospitals and healthcare providers worldwide
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Reliable Efficacy: Proven antihistamine with antiemetic and antivertigo activity
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Ideal for Emergencies: Ready-to-use vials ensure swift symptom management in urgent care
Directions for Use
For administration by healthcare professionals only. Always follow prescriber’s orders and institutional protocols.
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Check the vial label and expiration date before each use.
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Inspect the solution for clarity; do not use if cloudy or contains particulates.
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Withdraw the prescribed dose using aseptic technique. Standard adult dose is 50 mg (1 mL), but individualize per patient needs.
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Administer IM or slow IV as ordered by the physician.
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Repeat dosing as directed: May be repeated every 4-6 hours if needed, not to exceed recommended daily limits.
- Monitor patient for therapeutic effect and side effects.
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Dispose of used materials in appropriate sharps containers as per protocol.
Specifications
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Brand: Fresenius Kabi
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Generic Name: Dimenhydrinate Injection, USP
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Strength: 50 mg/mL
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Dosage Form: Injectable solution
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Volume: 1 mL per vial
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Packaging: 25 multiple dose vials per tray
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NDC: 63323-0366-01
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Product Number: 030602
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Administration: Intramuscular (IM) or intravenous (IV) injection
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Sterility: Sterile, pharmacy grade
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Latex-Free: Yes
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Prescription Required: Yes
Side Effects
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Common: Drowsiness, dry mouth, blurred vision, dizziness, mild headache
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Possible: Restlessness (especially in children), confusion, constipation, or difficulty urinating
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Serious (rare): Allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing), rapid or irregular heartbeat, low blood pressure
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Notify a healthcare provider immediately if experiencing severe or unusual symptoms.
Warnings & Precautions
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For professional use only; not for self-administration
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Contraindicated in patients with: Known hypersensitivity to dimenhydrinate or similar antihistamines, premature infants, or those with certain respiratory disorders
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Caution in: Elderly patients, children, those with glaucoma, asthma, enlarged prostate, liver/kidney disease, or cardiovascular conditions
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May cause sedation: Avoid driving or operating heavy machinery after administration
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Use in Pregnancy or Breastfeeding: Only as prescribed; consult with healthcare provider
- Keep out of reach of children
- Store in original packaging, protected from light, at recommended temperature
Why Choose Dimenhydrinate Injection by Fresenius Kabi?
- Trusted hospital-grade antiemetic for effective and immediate relief
- Multiple dose vials for efficiency and convenience in high-volume settings
- Essential for emergency departments, surgery centers, and travel clinics
Order Dimenhydrinate Injection 50 mg/mL Multiple Dose Vials 1 mL x 25/Tray by Fresenius Kabi (NDC: 63323-0366-01, Product Number: 030602) for instant, reliable control of nausea and motion sickness—trusted by healthcare providers for quality and results.